Pictured above is a section of a large infographic circulating reddit. It claims to show the full depth of the ocean at the Mariana Trench, scaled to the size of a human. The tiny dot in the upper-left corner represents a person.
Link via reddit | More Information about Mariana Trench Exploration
Pale Blue Dot
http://en.wikipedia.org/wiki/Pale_Blue_Dot
The pressures involved are a problem, yes, but we've already developed and are even currently using the technology to overcome that. I mean, for crying out loud, we set people down in the Challenge Deep back in 1960!
And really, the whole ocean is a tiny, infinitesimally small speck in the universe.
Makes you feel pretty small, doesn't it?