Scientists Breed Mentally Ill Mice

By onelargeprawn in Animals & Pets, Health, Science & Tech on Jul 30, 2007 at 9:11 am

mentally ill mouse Scientists have successfully created the world’s first schizophrenic mice in an attempt to gain a better understanding of the illness. It is believed this is the very first time an animal has been genetically engineered to have a mental illness.

The mice were created by modifying their DNA to mimic a mutant gene first found in a Scottish family with a high incidence of schizophrenia, which affects about one in every 100 people. The mice’s brains were found to have features similar to those of humans with schizophrenia, such as depression and hyperactivity.

Animal rights campaigners have condemned the research, calling it morally repugnant. What do you think?

Link – via A Welsh View


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  1. FB
    Jul 30th, 2007 at 9:28 am

    That picture is highly uncalled for. I know people suffering from schizophrenia.

  2. cnr
    Jul 30th, 2007 at 10:22 am

    My mom had manic depression, I don’t think testing on animals is right, for makeup and such. But if this could honestly help people, I’m all for it. But you know what will happen, they will make a huge discovery and make a pill that costs a fortune out of reach of most of the mentaly ill.

  3. Jenny
    Jul 30th, 2007 at 11:38 am

    That’s sick. Why do we even bother to protect animals from abuse under our laws when we plan on inflicting harm on them in labs to benefit ourselves?

  4. Chris
    Jul 30th, 2007 at 11:49 am

    the end justifies the means….

  5. meg
    Jul 30th, 2007 at 12:31 pm

    Get over yourself jenny

  6. Sid Morrison
    Jul 30th, 2007 at 12:35 pm

    Well, there was already a Krazy Kat. Now he has somebody to chase! That mouse is whack!

  7. Atomic
    Jul 30th, 2007 at 12:37 pm

    Ok Jenny, let’s stop the research on the mice. Here is another option; let’s do it to people instead. Or, let’s do nothing and let people continue to suffer from a dreadful mental illness.

    Do either of those options sit better with you?

  8. jackbillfredbobstevedave
    Jul 30th, 2007 at 12:47 pm

    screw the mice! sounds like a good idea to us!!

  9. V
    Jul 30th, 2007 at 12:56 pm

    I caught some mice in those sticky traps the other day at my house and experimented on them. They didn’t seem to mind and I don’t think they even had schizophrenia!

  10. Jennie
    Jul 30th, 2007 at 1:56 pm

    As a person with bipolar disorder I would not wish this or any other illness on any living creature with the potential of being healthy. I’m sorry if that offends the sensibilities of those of you who find it difficult to deal with us.

  11. Sid Morrison
    Jul 30th, 2007 at 2:35 pm

    Atomic (facetiously) suggests experimenting on people… That’s basically what old man Joe Kennedy was doing when he had his depressed daughter Rosemary lobotomized to control her mood swings and avoid publicly embarassing the politically-minded family.

    She went from being just slightly dim and moody, but otherwise normal, to being completely incapacitated, incontinent, and unintelligible. They later tried to claim that she was mentally retarded (her condition proved useful for her sister’s Special Olympics organization). Those who knew her prior to the operation (or read her writings) know the real truth.

  12. Celeste
    Jul 30th, 2007 at 2:54 pm

    I disagree with animal testing as a whole. If animals are close enough to us biologically to test, then how is it morally acceptable to test on them? Makes no sense.

  13. L
    Jul 30th, 2007 at 3:19 pm

    It’s kind of cruel. Especially when they don’t even know if it will apply to human brains.

  14. Terry
    Jul 30th, 2007 at 4:14 pm

    Why don’t these so-called scientist get a grasp of archeology and realise that symptoms of schizophrenia (such as hearing voices and visions) are not only normal in many cultures but even desirable as voice hearers are seen as having close links to the spirit world.

    Some of us are wise enough to see the our christian materialist culture for what it is, a social construct!

    Schizophrenia (and mental illness) is, a means of reality enforcement and social control applicable to westernised culture.

    I am an indigenous Australian, my culture is over 60,000 years old. The scientists should learn about our culture and our dream time.

    I feel sad for the tortured animals. :-)

  15. Ben
    Jul 30th, 2007 at 4:37 pm

    You know, if they could apply this to computers, we’d have some truly impressive artificial intelligence.

    I’d say that as soon as the mouse complained, you should stop experimenting on it. Common courtesy.

  16. andrew
    Jul 30th, 2007 at 7:00 pm

    Terry : hearing voices is neither normal nor desirable in many cultures. I for one know that I would not like to hear voices. Smoking is normal and desirable in some cultures, but that doesn’t mean that we should stop looking for a cure to lung cancer.

    Ben : What would constitute complaining? speaking in proper English and asking kindly to be let go? would this apply to all mice or just the one?

    I think seeing animals in pain due to testing is a good sign that they would ask to be let go if they could.

    That being said, if it helps more than it hurts (hurrah utilitarianism)

  17. Jennie
    Jul 30th, 2007 at 7:13 pm

    hurts whom?

  18. DW
    Jul 30th, 2007 at 9:02 pm

    I just want to know how one decides a mouse is schizo? What does a mouse like that act like???

  19. Terry
    Jul 31st, 2007 at 1:03 am

    DW,

    No lab test exists to identify a single mental illness in humans. No lesion has ever been found for any mental illness.

    Check out the Rosenhan experiment on wiki to see just how accurate schizo diagnosis is. LOL This mouse experiment is just junk science!

    Andrew,
    I think you should read a few anthropology studies and broaden your horizon.

  20. Rosi
    Jul 31st, 2007 at 6:36 am

    It’s just a mouse! Honestly, my friend’s mice were so stupid that when its tail got caught underneath another one (which was sleeping) it tried to chew it off. You’re legally allowed to kill mice anyway… and their life expectancy in these research facilities is usually longer than their life expectancy in the wild. Some of them are even kept as pets after the experiments are over. Also there is the fact that they’re helping humans (who are way smarter and self-aware), maybe even people you know someday, to have better lives and live longer. So the real question is if you value the life of a human more than a mouse. If you choose the mouse, there is seriously something wrong with you.

  21. Jennie
    Jul 31st, 2007 at 1:13 pm

    There is something wrong with me, medically speaking but I still choose the mouse. It’s purpose is not to be experimented on. Your friend mice were probably stupid due to generations of commercial inbreading not their inherent nature. Remember all those mazes. They are great problem solvers. Mice are extremely intelligent, emotional, & social. They bond with their companions (regardless of species).

    Most of all, while people and animals suffer alike, physiologically, different species vary so vastly that data can’t be accurately extrapolated from one species to another. Even chimpanzees, our closest living relatives—with whom we share 99 percent of our DNA—don’t sicken when infected with many diseases that are fatal to us.

  22. andrew
    Jul 31st, 2007 at 7:08 pm

    A bit late getting back to the party, let’s see if anyone’s still around:

    On the question of hurting versus helping I’m speaking in a utilitarian sense. Applying this to the whole group of living beings on a net “pleasure/pain” scale. If we can test a few mice, which have limited levels of self-awareness (if any) in order to help all human schizophrenics for the rest of human history live better lives I would say it is probably worth it.

    And on anthropology: Actually, I have done a lot of reading on different cultures. I know and understand that hearing voices is a good thing in a lot of cultures, but as I said, “it is neither normal nor desirable in many cultures”. This would include many modern western cultures, and many more I’m sure you can think of. notice I said many, not all or most.

    That being said, I am not a fan of cultural relativism. it is too easy of an answer to a much more complex question, and also allows for some startling holes in “common sense” morality. Unfortunately, it seems that for people who understand and study other cultures (like myself) but don’t blindly accept their beliefs as true (via cultural relativism) are often told that they need to “broaden your horizon”.

  23. Bob-O
    Aug 1st, 2007 at 10:22 am

    I honestly would condone the killing and tourtue of every mouse in the world if it saved just ONE human. Call me mean or evil or just plain disgusting, but I personally believe that a human life is worth far more than that of a mouse.

  24. PaperMathers
    Aug 1st, 2007 at 9:26 pm

    There is no such thing as mental illness.
    These mice have been possessed by Thetans.

  25. Sharky
    Aug 23rd, 2007 at 5:17 pm

    What’s so cruel about it? We bred Mentally ill mice, They were born that way their not gonna know any different or care! Expirimenting on animals for fun is wrong but if it’s to improve or save human lives then why not


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