Street artist E. Lee doesn't just paint his works anywhere, but integrates them into the surrounding scenes. In this case, he made use of the pre-existing "please back in" sign in his painting in Chicago of Wile E. Coyote trying to trap the Road Runner.
It's not the first time that E. Lee has collaborated with Wile E. We've previously seen them try and fail to lure the Road Runner with a trap baited with free bird seed. That failed, as this one surely will, too. But Lee is loyal to his friend. He explains:
I love Wile E Coyote. And I’m sure most people trying to make a living in a creative field see a little of themselves in him. I think it’s important that we find humor in our plight of constantly having to create, optimistically making plans and then seeing those plans rarely work the way we’d hoped.