Scientists have discovered that one protein is linked to different diseases including depression, obesity, and chronic pain.
Called the FK506-binding protein 51 or FKBP51 for short, not only is it connected to the diseases mentioned above but it could also have applications for diabetes, alcoholism, and brain cancer.
"The FKBP51 protein plays an important role in depression, obesity, diabetes and chronic pain states," says Felix Hausch, Ph.D., the project's principal investigator.
"We developed the first highly potent, highly selective FKBP51 inhibitor, called SAFit2, which is now being tested in mice. Inhibition of FKBP51 could thus be a new therapeutic option to treat all of these conditions."
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