Researchers bathed lab-grown human endothelial cells—the type that line blood vessels—in varying concentrations of squalamine before introducing dengue virus. At the highest concentration of the chemical, none of the human cells became infected, nor suffered any visible ill effects from the squalamine.
Researchers also tested squalamine’s ability to prevent replication of the hepatitis B and D viruses in cultured human liver cells. In cells treated with squalamine, viral replication was reduced 10-fold.
Squalamine has antibiotic, fungicidal, and anti-protozoan properties. It kills a wide variety of pathogens and one study found it could be used to treat multidrug-resistant bacteria. Researchers are also investigating its ability to treat cancer and fight macular degeneration.
Link -via Discover | Image Credit OCVA