Science is a field based largely on theory and experimentation, which is why you have to be pretty darn certain you are right if you’re willing to test your ideas on yourself. For example, in the picture above:

In 1929 in the basement of the Eberswaled Hospital in Germany, surgical resident Werner Forssmann inserted a ureteral catheter tube into his elbow, feeding it through a vein up to his heart. He used a mirror as his assistant, since he had restrained his nurse to the operating table. He then took an x-ray of his chest (at left) to determine the catheter had indeed made it to the right atrium.

Learn about more dedicated, and brave, scientists over at Mental Floss.

Link

Her most famous study, conducted in twelve different New York City schools along with Claudia Mueller, involved giving more than 400 fifth graders a relatively easy test consisting of nonverbal puzzles. After the children finished the test, the researchers told the students their score, and provided them with a single line of praise. Half of the kids were praised for their intelligence. “You must be smart at this,” the researcher said. The other students were praised for their effort: “You must have worked really hard.”

The students were then allowed to choose between two different subsequent tests. The first choice was described as a more difficult set of puzzles, but the kids were told that they’d learn a lot from attempting it. The other option was an easy test, similar to the test they’d just taken.

When Dweck was designing the experiment, she expected the different forms of praise to have a rather modest effect. After all, it was just one sentence. But it soon became clear that the type of compliment given to the fifth graders dramatically affected their choice of tests. When kids were praised for their effort, nearly 90 percent chose the harder set of puzzles. However, when kids were praised for their intelligence, most of them went for the easier test. What explains this difference? According to Dweck, praising kids for intelligence encourages them to “look” smart, which means that they shouldn’t risk making a mistake.

A further experiment showed how fear of failure can inhibit learning. Read about all of them at The Frontal Cortex. Link

(Image credit: Flickr user mujalifah)

Tripping Elephants On Parade

Image via http2007 [Flickr]

While many test animals are killed in the name of research, many of them are at least being used to investigate potentially life-saving drugs. Perhaps the saddest and most spectacular failure of any animal-based experiment occurred in 1962, when Tusko the elephant (not the one pictured) was given LSD simply for the sake of seeing how the magnificent beast would react to such a substance.

Unfortunately, the researchers, Louis Jolyon West and Chester M. Pierce, had no idea how much LSD it would take to dose an elephant. Rather than erroring on the side of safety, the doctors decided that they didn’t want to have to do the experiment again just because they underdosed the elephant the first time. They ended up deciding to give Tusko 297 milligrams, which is about 3000 times the dosage a human takes, despite the fact that an elephant weighs about 90 times more than the average human.

After being dosed, Tusko immediately started running around in his pen and soon lost control of his movements, eventually collapsing to the ground and going into seizures. To counteract the LSD, the doctors gave the elephant 2,800 milligrams of an antipsychotic. The drug reduced his seizures slightly, but didn’t stop them. After another hours, the doctors decided to give Tusko a barbiturate to calm him down, but it didn’t help. He died a few minutes later.

Two other elephants were later dosed with the drug and suffered no ill effects. Ultimately, the doctors that dosed Tusko summed up their experiment in Science by saying, simply, “It appears that the elephant is highly sensitive to the effects of LSD.” Even so, it is still unclear whether or not Tusko died from the acid or a combination of the three drugs given to him that day.

The Monster Study

The effects of positive vs. negative reinforcement have fascinated scientists and parents for hundreds of years. Unfortunately, testing on a group of unsuspecting orphans isn’t the best way to find out. In 1939, Doctor Wendell Johnson of the University of Iowa and his assistant, Mary Tudor, selected 22 children from an orphanage in Iowa. Ten of the children had stutters and the rest spoke just fine.

The stutterers were put in two groups, group IA that was to use positive reinforcement and other, group IB, that was to receive negative reinforcement. The non-stutterers were also broken into two groups, group IIB, that was told they spoke fine, and group IIA, who were told they were starting to stutter and needed to avoid making mistakes at any cost. The goal was to get those in group IA to stop stuttering and those in group IIA to start stuttering.

The impact on group IIA was exactly what the doctor had hoped for. The entire group started falling behind on their school work. The children started to second-guess their speech abilities and many stopped talking at all. One girl ran away shortly after the experiment ended. While Mary Tudor visited the orphanage three times after the experiment was over, attempting to convince the children that they didn’t have any speech problems, the damage was already done. Although none of the kids became stutterers, many of the children retained speech problems their entire life and most were reluctant to speak. In 2007, six of these children were awarded $925,000 in a lawsuit against the state for the university’s role in the experiment.

The study has since been dubbed “The Monster Study” by the public and scientists alike who were disgusted with the doctor’s methods.

The Baby Born A Chimp

Image via BoingBoing

There have been ample stories of human children being raised by other species and eventually becoming more like that animal than an actual human. If the process could go one way, Winthrop Kellogg was sure that it could also go the other, particularly if the animal involved was one of our closest genetic cousins.

In 1931, Kellogg received a grant for his experiment and the timing couldn’t be better –his wife just had a baby boy, David. This would give them the unique opportunity to raise a baby chimp, named Gua, right along side a human baby. It didn’t take long for the babes to bond and become best friends.

Kellogg and his wife took impeccable notes on their two “children” noting their physical changes, emotions and how they scored on small intelligence tests. The chimp scored notably higher on the intelligence tests due the fact that the species matures faster than human babies.

Gua picked up quite a few human behaviors, such as walking upright and eating with a spoon, but she failed to learn how to speak and learn simple repetition games, like patty cake. Her emotions were also much less predictable and inclined to change at the drop of a hat.

Unfortunately, the experiment really started to go wrong when little David started to become more chimplike than Gua became humanlike. He only learned a few simple words and often took to making chimp howls when he wanted something.

After only nine months, the Kelloggs gave up on Gua, concerned that David would fail to grow up like a normal human child. In the years since this project, plenty of people have adopted chimps as babies, proving beyond a doubt that the animals can never act completely human –even if they are adorable in overalls.

Yellow Fever Fever

Doctor Stubbins Ffirth observed that yellow fever was prominent during the summer, but receded as winter approached and made the mistaken conclusion that this meant the disease was not contagious. The fact that he never caught the disease after constant exposure to patients with the malady further inspired him. In order to prove the disease was non-contagious, Ffirth decided he needed to expose himself to all types of bodily fluids secreted by yellow fever victims. He drank the vomit of the victims, he injected it into his veins, he dripped it into his eyes and he inhaled the fumes from the vomit. Through it all, he never did manage to contract the disease.

Rather than admitting that he made his point or moving on to testing on other people, Ffirth realized there were far more body fluids for him to experiment with. He used blood, urine, saliva and perspiration. Even after all of these tests, his still managed to resist the disease. Unfortunately, Ffirth failed to take into account the different stages of the disease. His samples all came from persons who were in the late stages of the malady, and were, thus, no longer contagious. Had he experimented with samples from people who only recently contracted the disease, his results likely would have been a whole lot different.

As for the observation that the disease disappeared during the winter months? He was right about that, just wrong about the cause. Yellow fever is caused by a RNA virus that is spread by mosquitoes. That’s why it was so much more common during the humid summers on the East Coast. Fortunately, before word of Ffirth’s research spread, locals believed the disease was spreading through the waterways and Philadelphia introduced a closed water system that helped eliminate cisterns and barrels full of water that served as mosquito breeding grounds during the summer.

A Baby In A Box

Image via Silly Rabbit [Wikipedia]

This is perhaps the only science experiment in this list that went totally right –up until the idea was released to the public. Doctor Fredric Skinner had a lot of trouble bending down into his baby’s crib to pick her up. When his wife became pregnant with a second child, he worked hard to develop a more comfortable and elegant solution. What he came up with was a “baby box.”

The box was about six feet tall and lifted the baby up about three feet high. The sleeping area was a shallow bin with a safety glass window that allowed it to see the outside world while keeping it safe. The box provided the baby with a heater, humidifier and an air filter so the baby always had fresh, warm air. It was also well-insulated to help keep out loud noises. Parents could lift the baby out of the device without back strain. The baby stayed warm, so it didn’t need clothes or blankets that could get tangled up and become a hazard. Plus, this also meant less laundry for the parents. The mattress was made of a sheet of canvas held in place by two rollers, so when it got dirty, they just had to roll it to reveal a new, clean section. All in all, the device had tons of benefits and the doctor’s baby responded to the device quite well.

Unfortunately, Skinner decided to bypass academic journals and send an announcement of his achievement through Ladies’ Home Journal. While the title of the piece he sent was “Baby Care Can Be Modernized,” editors decided to change it to “Baby In A Box.” This one little change was largely responsible for the public backlash against Skinner’s revolutionary idea. People accused the doctor of caging his child up like an animal, raising a child like a vegetable garden and gaining inspiration for his idea from a grocery freezer case.

While Skinner did want to run formal experiments comparing ten children who were raised with the box and ten children who were raised in a crib to see if either group had any disadvantages long term, the public outrage against his work led him to back off on his project. His own daughter did seem to come out just fine in the end, becoming a successful artist in London. Eventually, Skinner did get a manufacturing deal, selling a few hundred units of “The Air Crib,” but the head of the manufacturing company soon passed away, leaving the idea to die in the process.

Now, obviously, there are far more science projects gone wrong than just these. If you’ve heard any stories, feel free to share them in the comments. Or let us know what you think about the projects. Personally, I think the baby box is a great idea and I would love to have had one when I have a kid.

Sources: Elephants On Acid And Other Bizarre Experiments, Wikipedia #1, #2, #3, Listverse

Koichi Wakata, a Japanese Astronaut who is working aboard the International Space Station was given the task to perform a few silly experiments in Zero-G requested by the Earth People of Japan. They consist of the mundane such as performing push-ups, squirting water from a tube, backflips and so forth but then some of them are bizarre like the “flying magic carpet” request! Oh, how I wish I were in space like Koichi and the other fine men and women of the ISS crew! I would see to it if I could perform the moonwalk in Zero-G!

The 16 space experiments in a nifty list – Link (also from Pink Tentacle)

Via – Pink Tentacle

Throughout history there have been a few lost souls who have taken the beauty of science and instead of honoring it, twisted it and contorted it into something evil.  

Science, we are informed by conscientious historians of the discipline, is something that comes to us without anything we might call a “moral imperative” as to what we should or should not be doing with the knowledge. In fact, science has often been described as an “amoral” enterprise, which can be put to evil uses just as easily as good ones. Scientists themselves bear no responsibility to ensure how their discoveries are used by others.

But what if the scientist himself is a diabolical mad man?

Link – via thrivecore

From the Upcoming ueue, submitted by greeneagle.

Sex, Drugs and Science

If this first group of studies show us anything, it’s that scientists are as drugged up and crazy as the junkies up the street from me.

Elephants on Acid:

If you were going to see the effects of LSD on an elephant, wouldn’t you start with smaller doses and progressively increase the dosage until there was a noticeable change in their behavior? I sure would. But the researchers on this one aren’t like you and me.

Instead the researchers working on this one started off by injecting the poor beast with 3000 times the dosage needed for an average human, despite the fact that elephants weigh around 50 times what the average human weighs. Within two hours, the animal died. The scientists defended their actions by saying they had used LSD plenty of times and were sure it was safe. They then concluded, “elephants are highly sensitive to LSD.”

Apparently another scientist found their results to be suspicious, so he gave elephants LSD in their water. In his study, the elephants acted a little funny, but were totally fine.

Source

Turkey Arousal:

We’ve all heard stories detailing how stupid turkeys are -like the one that says they’ll drown if you leave them in the rain. Well, some of those turkey stories may be bogus, but two Penn State researchers discovered that turkeys are so stupid they can be trained to be aroused by little more than sticks.

Their experiment consisted of creating a model female turkey that could be progressively deconstructed. The scientists would then gauge the turkey’s interest in the “female” and then remove some parts of her body and try again. They were expecting the birds would lose interest after is was stripped down enough. Surprisingly, the turkeys were aroused even when the model became little more than a stick with a head. I guess this not only shows how stupid turkeys are, but how perverse they are too.

Source | Photo Via Vicki’s Nature [Flickr]

Semen As an Anti-depressant?

I always thought scientists were supposed to be unbiased. I mean, if you’re hoping for certain results, might that affect your research? Obviously these researchers bypassed that concept, by attempting to prove that semen works as an antidepressant. They decided to study this theory by interviewing college women who were sexually active. Their conclusions proved that women who had sex without condoms were less depressed than women who used them.

Of course, their research was extremely preliminary and they didn’t even bother to take into account additional factors, like the fact that women not using condoms are more likely to be in serious

relationships. It doesn’t take a scientist to figure out that this might play into someone’s relative level of happiness. But like I said, this study was about as unbiased as all those tobacco company ones that couldn’t connect smoking with cancer.

Source | Photo Via Zen [Flickr]

Paging Dr. Obvious

The rest of these studies are amazing -in that someone actually bothered to research things so obvious:

Head Banging is Bad For You:

Who would have ever thought that aggressively and repeatedly throwing your head up and down would be bad for you? Gee, I never would have imagined that spinal damage and brain trauma could have resulted from head banging. Obviously, I’m being sarcastic. After years of dating a metal head, I can assure you that head banging can certainly make you retarded…or at least, it doesn’t help your intelligence at all.

The only good thing researchers found was that head banging is unlikely to leave you unconscious. What is really funny is the researcher’s suggestions for the metal genre. They suggest metal bands play more

mellow tunes and less “beat oriented” music. They also urged label to place anti-head banging warnings on their cds. Oh, and listeners were advised to start listening to “adult-oriented rock” instead of heavy metal. Yeah, that’s gonna happen real soon.

Source | Photo Via Cayusa [Flickr]

Male science nerds likely to be virgins:

Hmmm, who is most likely to be a virgin, a party-girl, a jock, or a nerd? Think about it. No surprise here; male science nerds between 16 and 25 are the most likely to not have had sex.

At least the study provided some legitimate reasons for this statistic, rather than the typical “nerds are pimply and boring” theories of popular media. The study reasoned that these nerds were the population segment least likely to be in situations where they would meet potential lovers. Apparently, doing homework and going to the library doesn’t help you meet chicks. Hey, at least they’re being productive. Interestingly, female art students were the most sexually active.

Source | Photo Via Miss604 [Flickr]

Bullies Like Seeing Pain:

If bullies were compassionate they would sit around crying whenever they picked on people. The fact that they don’t do so might just indicate that they are mean. Why did anyone need to set up a study to confirm that bullies enjoy seeing other people in pain?

An interesting thing about this study is that it was the first time anyone used fMRI to evaluate how respondents reacted to different emotions. Instead of being empathetic like the brain of a normal person, bullies mind’s activate their reward centers when they see videos of other people being picked on.

Source | Photo Via ZZClef [Flickr]

Television Viewers Are Unhappy:

It’s common knowledge that television and other forms of entertainment are a way for people to escape their problems. If you run home to watch tv instead rather than hanging out with friends, you might be unhappy. Did we really need a scientist to tell us that people who socialize are generally more happy than people who sit at home watching tv all day? What’s more crazy is that they needed over 30 years of data to back up their claims. The only unique thing the study discovered was that many viewers are actually addicted. (Marx was right about television, is this evidence that the scientists are commies?):

“Addictive activities produce momentary pleasure and long-term misery and regret,” said Steven Martin, co-author of the study. “People most vulnerable to addiction tend to be socially or personally disadvantaged. For this kind of person, TV can become a kind of opiate in a way. It’s habitual, and tuning in can be an easy way of tuning out.”

Funny, I’ve was using the audio/visual equivalent of heroin the whole time I was researching this. I swear I could quit any time.

Source

Now that I’ve written this, I think I’ve got a couple of ideas I could get funded. For example, are people happier when they’re warm at home or cold in the middle of nowhere? Or maybe I could find out if donkeys really die when they take a bunch of cocaine and other drugs at a bachelor party. Do you guys have any ideas for awesome studies?