When Craig Venter created a synthetic microbe, he inserted a passage from James Joyce. Guess who’s upset? Joyce’s estate, claiming copyright infringement:
In order to distinguish their synthetic DNA from that naturally present in the bacterium, Venter’s team coded several famous quotes into their DNA, including one from James Joyce’s A Portrait of the Artist of a Young Man: “To live, to err, to fall, to triumph, to recreate life out of life.”
After announcing their work, Venter explained, his team received a cease and desist letter from Joyce’s estate, saying that he’d used the Irish writer’s work without permission. ”We thought it fell under fair use,” said Venter.
Another step in the quest to create life has been made, as scientists successfully transformed one bacteria into another by replacing it’s DNA with a related species’. Now, scientists are setting their sights on creating entirely new microbes with unique genome sequences, from scratch.
Dr Venter likened it to “changing a Macintosh computer into a PC by inserting a new piece of software” and stressed it would be more difficult in other kinds of cells, which have enzymes to snip the DNA of invaders.
But he said to achieve the feat, without adding anything more than naked DNA, “is a huge enabling step.”
“It’s a necessary step toward creating artificial life,” added microbiologist Fred Blattner of the University of Wisconsin, Madison.
Dr Venter said that, in the light of this success, the culmination of a decade’s work, he will be attempting the first transplant of a lab-made genome to create the first artificial life “within months.”
From the Upcoming
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