The HIV antibodies were discovered in the cells of a 60-year-old African-American gay man, known in the scientific literature as Donor 45, whose body made the antibodies naturally. The trick for scientists now is to develop a vaccine or other methods to make anyone's body produce them as well.[...]
HIV is a highly mutable virus, but one place where the virus doesn't mutate much is where it attaches to a particular molecule on the surface of cells it infects. Building on previous research, researchers created a probe, shaped exactly like that critical site, and used it to attract only those antibodies that efficiently attack it. That is how they fished out of Donor 45 the special antibodies: They screened 25 million of his cells to find 12 that produced the antibodies.
Donor 45's antibodies didn't protect him from contracting HIV. That is likely because the virus had already taken hold before his body produced the antibodies. He is still alive, and when his blood was drawn, he had been living with HIV for 20 years.
The De Montfort University graduate used a ratchet system built into the frame of the bike to allow it to wrap around a pole, enabling the lock to be wrapped through both wheels and the frame.
Securing all the bike's components within the lock was his aim in creating the new bike. It also allows the bike to be stored in small spaces.
The frame can be ratcheted tight to allow the bike to be ridden like a normal bike, but it can be quickly loosened to allow the frame to be bent back on itself.
Series creator (and main voice) Mike Judge is reportedly putting together 30 new episodes to continue the adventures of his articulate animated heroes.
Specifics of timing and format are still being resolved, but the process is underway.
Wives spend 7,920 minutes a year nagging their husbands about household chores, their drinking and their health.
This equals two-and-a-half hours of earbashing each week - which totals 11 hours a month or five-and-a-half days a year.
A study of more than 3,000 people carried out by health campaign group Everyman concluded the most common subject women nagged their partners about was not helping to tidy the home.
If earth ceased rotating about its axis but continued revolving around the sun and its axis of rotation maintained the same inclination, the length of a year would remain the same, but a day would last as long as a year. In this fictitious scenario, the sequential disappearance of centrifugal force would cause a catastrophic change in climate and disastrous geologic adjustments (expressed as devastating earthquakes) to the transforming equipotential gravitational state.
The lack of the centrifugal effect would result in the gravity of the earth being the only significant force controlling the extent of the oceans. Prominent celestial bodies such as the moon and sun would also play a role, but because of their distance from the earth, their impact on the extent of global oceans would be negligible.
If the earth's gravity alone was responsible for creating a new geography, the huge bulge of oceanic water—which is now about 8 km high at the equator—would migrate to where a stationary earth's gravity would be the strongest. This bulge is attributed to the centrifugal effect of earth's spinning with a linear speed of 1,667 km/hour at the equator. The existing equatorial water bulge also inflates the ellipsoidal shape of the globe itself.
A whopping 6.5 hp, 32 mph, twin-throne action, and all the TP you can stand. Ain't America great?
We get emails like this all the time. "Come look at my toilet go-kart," they say. "It's the best toilet kart in the world," they say. "You'll love it, and you can flush your cares out the exhaust, and seriously, 32 freaking mph on a twin-pot crapcan that just might kill you if you look at it funny."
We could have all grown up with the Pan-Atomic Canal instead of the Panama Canal we know today. That is, if Operation Plowshare ever took off (the government's term for using nukes in construction, including the highway-blasting idea above and the harbor you're about to read about below). Building the Panama Canal was a long, deadly process. Also many ships are too big to traverse the canal. To make everything easier, why not just nuke it wide open? Well, radioactive fallout was a huge concern, and that fear even scrapped plans to use atomic bombs to create entirely new canals.
