simonster's Comments

In this study, the authors are looking primarily for fluorescent proteins, and the article says that "Scale renders mouse brain and embryos transparent while completely preserving fluorescent signals from labeled cells."

It seem like the goal here is to be able to take a mutant mouse that expresses a fluorescent protein in some subset of cells, crack its neck, take out its brain, put it in a solution of Scale, and then use a confocal microscope to create a 3D reconstruction of the distribution of the fluorescent protein. That's pretty cool...
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  • Member Since 2012/08/04


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