Cancer research has made strides in trying to understand how these cells mutate as well as how our bodies fight off these cancer cells. Recently, a collaboration between researchers from Weill Cornell Medicine and New York Genome Center have developed tools that can detect and track the epigenetic evolution of cancer.
Described in papers May 15 in Nature and April 23 in Nature Communications, the new approach allows researchers to isolate individual cancer cells sampled from patients and map the epigenetic marks on the cells’ chromosomes. Epigenetic marks are chemical marks on DNA or on DNA-support proteins (called histones) that help control which genes are switched “on” and which are switched “off” in a cell. They essentially program what the cell does and what it doesn’t do.
The first step that researchers need to know about the mutation of cancer cells is exactly where it starts, what the exact triggers are, and how the mutated cells respond to various treatments. Their findings can also help in formulating treatments that would target the specific cause of the cancer as well as prevent them from spreading. But it will be a challenge.
Landau and other researchers have previously shown how a diversification occurs at the genetic level in cancers, such that different cells within a tumor contain distinct sets of gene mutations.
“This enormous diversity within each cancerous cell population means that in each patient, we’re dealing with thousands of variants of the cancer rather than just one entity, and all this variation increases the cancer’s potential to adapt to challenges such as drug therapy,” said Landau, who’s an oncologist at NewYork-Presbyterian/Weill Cornell Medical Center. “Here we’re extending that concept to show that there is epigenetic diversity as well.”
(Image credit: Susan Arnold/National Institutes of Health, Wikimedia Commons/Public Domain)
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The man lacked imagination and could have added some cherubs or pixies, etc.. 0r England is probably still laughing since he did end up with most of what Davis owned in life and obviously didn't advise on style and grace as well as refrain from offering moral opinions. He was not going to spoil the fun.
I think it's not too late to add some angels and fairies........... Maybe the family dog or why not Mr England. Only in America.
After all the whole point of an epitaph is for the deceased to be remembered, and it's common practice around the world - many of the World Wonders are essentially epitaphs (pyramids of Giza-Egypt, Taj Mahal in Agra-India)
sweet
actually pretty lame but oh well
Is love so dead in this world these days?
No most of the US is not this wierd. Only in Kansas.
I've lived there and the wierd people of California have nothing on the wierd red necks of Kansas. This is really strange and a huge waste of time and money.
Please do not judge the entire U.S. on Kansas.
Please. No, really.
ages. I am surprised that no ghost stories have been linked to it(or are there?)
At first glance, it looks like an odd grave featuring
a dinner party or something like that.