Peanut Allergy Breakthrough: Understanding the Underlying Immune Defense Mechanisms for Treatment

Being allergic to certain types of food is annoying. You can't enjoy those food and you will always have to be on the look out for food that may have them as ingredients. It makes eating less of an enjoyable experience.

The best way to treat allergic reactions is by taking antihistamines and allergy shots for serious cases. However, scientists say that they may have made a breakthrough in understanding allergic reactions, starting with peanut allergies.

For their study, published in Proceedings of the National Academy of Sciences, scientists recruited 16 patients who were allergic to peanuts. They tested serum from the participants’ blood to identify where the IgEs binded with peanut proteins.
Next, the scientists developed inhibitors, enzymes which bind to other enzymes to reduce their activity. Those molecules, which they named covalent heterobivalent inhibitors, were found to stop allergic reactions by stopping IgES from latching on to peanut proteins.

(Image credit: Brittany Colette/Unsplash)


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