Brad Slattery made Super Pixel Bros., a version of Super Mario Bros. that is played with 64 alternating lights. The whole design is quite minimal. There's a 8X8 LED matrix, a digital display, and controller buttons mounted onto a circuit board. There are multiple levels in the game, each of which is 120 pixels wide. Mario is represented by a simple yellow dot.
http://www.bradsprojects.com/electronics/Bradsprojects-SuperPixelBros.html -via Bit Rebels