American Inventor Spot has a list of 10 purses they claim to be manly enough that a guy wouldn't feel embarrassed holding them. The purse above, created by Yael Mer to look like it contains a severed human head (eek!), is #9 on their list.
Link - Thanks Michelle!
For other odd handbags, check out the NES controller purse, a purse made out of real toads, or a purse made from juice boxes.