8% of Human DNA Comes from a 40 Million Year-Old Virus

A team of scientists led by Keizo Tomonaga of Osaka University determined that a virus dating from 40 million years ago is embedded in human DNA. This infection, known as the bornavirus, might be the cause of schizophrenia and passes from generation to generation inside human cellular nuclei, filling out 8% of human genetic code:

The assimilation of viral sequences into the host genome is a process referred to as endogenization. This occurs when viral DNA integrates into a chromosome of reproductive cells and is subsequently passed from parent to offspring. Until now, retroviruses were the only viruses known to generate such endogenous copies in vertebrates. But Feschotte said that scientists have found that non-retroviral viruses called bornaviruses have been endogenized repeatedly in mammals throughout evolution.

Bornavirus (BDV) owes its name to the town of Borna, Germany, where a virus epidemic in 1885 wiped out a regiment of cavalry horses. BDV infects a range of birds and mammals, including humans. It is unique because it infects only neurons, establishing a persistent infection in its host's brain, and its entire life cycle takes place in the nucleus of the infected cells.


Link via io9 | Image: US Department of Energy

Just a side note about science reporting: I initially used an AFP article for this post, but wasn't pleased with its depth. So I looked for a meatier alternative in Science Daily. And what it said about the bornavirus discovery was substantially different from the AFP article.

I would guess that the Science Daily article was written by people with greater expertise, but in any event, it was a demonstration of how it pays to be skeptical of science journalism.
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Yeah, last week on NPR, it was mentioned that certain types of viruses (virii?) are very good at eating other creatures, chopping them up and incorporating some of their DNA or other structures, making them rapid evolution production machines on the viral and bacterial scale. Wish I had the link.
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"I'd like to share a revelation that I’ve had during my time here. It came to me when I tried to classify your species, and I realised that humans are not actually mammals. Every mammal on this planet instinctively develops a natural equilibrium with the surrounding environment; but you humans do not. Instead you multiply, and multiply, until every resource is consumed. The only way for you to survive is to spread to another area. There is another organism on this planet that follows the same pattern... a virus. Human beings are a disease, a cancer on this planet, you are a plague, and we... are the cure."
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aren't mitochondria also an old virus or bacteria or something?

just looked it up, i think they originated as a bacteria with whom we formed a symbiotic relationship. and by we, i mean cellular organisms at large.
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If this is correct, then the same virus must be in all the great apes' DNA and many of the old world monkeys' DNA, because 40 million years ago we shared a common ancestor with all of those primates.
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