Domestic cats normally come in solids, stripes, and patches (I have one of each). Some cats have been bred with spots, but the only naturally spotted house cat is the Egyptian Mau.
It is the only naturally spotted cat and has been used in the breeding programmes of other cat breeds, such as the British Shorthair, to provide the spotted gene the breeders require tointroduce the pattern to another breed.
This beautiful cat is part of the post “Fear Me, Love Me, Worship Me: A History of the Domestic Cat”. Link -Thanks, Roy Shechter!
(image credit: Flickr user Muffet)