Tanya suffers from a rare condition called acromegaly, where excessive amounts of growth hormone are released. Andre the Giant was a famous sufferer, as was Richard Keil who portrayed the famous villain "Jaws" in the James Bond movies.
In Tanya's case, a tumor wrapped itself around her pituitary gland, causing her condition. Unfortunately, despite several surgeries and medication, it has failed to stop the release of growth hormone. Today Tanya is a staggering 6'6" (2.0 m) and 480 pounds (218 kg), and still growing.
From the Upcoming ueue, submitted by Geekazoid.
My brother is 6'2" and weighs 150lbs and looks like he should be laying on his deathbed... nothing but skin and bones.