Irritating Side Effect of Cocaine Vaccine: It Causes Users to Take 10 Times as Much Cocaine as Before

By John Farrier in Health on Jan 6, 2010 at 12:00 pm

Last October, I posted about a drug that binds antibodies to cocaine to diminish its pleasurable effects in users. Well, it’s not working out terribly well because some users are responding by taking enough cocaine to overwhelm its protection:

Nobody overdosed, but some of them had 10 times more cocaine coursing through their systems than researchers had encountered before, according to Kosten. He said some of the addicts reported to researchers that they had gone broke buying cocaine from multiple drug dealers, hoping to find a variety that would get them high.

Thankfully, the drug was able to help some test subjects avoid cocaine.

Link via Popular Science | Image: US Department of Health and Human Services


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  1. Gauldar
    Jan 6th, 2010 at 12:16 pm

    The question I have regarding the people overusing after the vaccine is in effect, is if it’s a chemical issue, or just a habitual one in the patient.

  2. jermH
    Jan 6th, 2010 at 1:34 pm

    Science just got owned by human stupidity. This vaccine was clearly not idiot-proof.

  3. Tim Giachetti
    Jan 6th, 2010 at 1:51 pm

    Guess whose not coming to my next part?!?!

  4. Pietr
    Jan 6th, 2010 at 9:04 pm

    The National Institutes of Health (NIH) was created to cure human disease. That this inane and doomed concept was not only funded by the National Institute on Drug Abuse (NIDA) but also announced by its director demonstrates that the primary function of NIH today is to fund the expensive life styles of its experts.

    Addiction can be treated only by relieving craving, not by making addiction more expensive. Raising the price of one’s fix destroys the individual and societal goals.

    Treatment of addiction by increasing in an appropriate fashion the brain levels of two neuro-transmitters,dopamine and serotonin, is available now in what is called the PURSOR protocol. Unfortunately, while it is cheap, not toxic and employs only natural substances, levodopa and 5-HTP, it makes not a penny for PHARMA or the experts. Since the same protocol also remits depression and anxiety, it must be vigorously stopped. I should know, they effectively stopped me ten years ago.

    Pietr Hitzig

  5. Biffbiffley
    Jan 6th, 2010 at 10:06 pm

    They just let these people walk free?

    For christ’s sake.. weather or not they’re Vaccanated they’re still addicts and need guidence and help…*forheadpalms*

  6. Mike Lewis
    Jan 7th, 2010 at 1:52 am

    I wonder if the same thing will happen with the anti-smoking vaccine.

  7. ted
    Jan 9th, 2010 at 11:13 pm

    Misleading. It’s not compelling the users to take 10 times as much. Users have to take that much to get high again.

    Sounds like it builds up a resistance rather than curing the addiction.

  8. Cocaine Treatment
    Jan 25th, 2010 at 3:35 am

    In the past ., Cocaine appears to damage the brain’s natural reward mechanisms one of Director of the Brain Institute at Mount Sinai School of Medicine and a member of the Dana Alliance for Brain Initiatives. “You continually blast the reward circuit and it becomes less sensitive. So the person has this blunted reward circuit, doesn’t feel good at all, and soon the fastest way just to feel normal is to take the drug.”


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