Tooth Grown from Stem Cells

By Miss Cellania in Science & Tech on Aug 5, 2009 at 12:02 am

Scientists from the the Tokyo University of Science used mouse stem cells to grow a new tooth that worked like a charm in a mouse’s mouth. The cells were grown in a lab dish until a tiny tooth “bud” formed. It was then transferred to the jaw of a mouse where a tooth had been removed. The new tooth erupted through the gum in about five weeks, and was fully grown in seven.

The researchers, who repeated the experiment many times, also showed that the new, bioengineered teeth were fully-functional.

Dr Kazuhisa Nakao said: ‘Every bio- engineered tooth erupted through the gum and had every tooth component such as dentine, enamel, pulp, blood vessels, nerve fibres, crown and root.’

Importantly, the rodent recipients had no trouble eating.

If the technique can be used in humans, dentures may eventually be obsolete. The tooth shown in the picture also had a green fluorescent gene so it could be seen easily. Link -via Digg


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  1. Kalel
    Aug 5th, 2009 at 12:32 pm

    I just had an image of old folks with rat teeth.

  2. coconutnut
    Aug 5th, 2009 at 2:14 pm

    This sounds like a pretty important breakthrough for amputees/oldpeople. Are limbs much harder to grow than teeth?

  3. big hairy guy
    Aug 5th, 2009 at 6:02 pm

    That green flourescent gene should be spliced into something useful, like fishing worms.

  4. stormie24
    Aug 5th, 2009 at 7:10 pm

    this reminds me of happy potter.
    and big harry guy, forget the worms! glowing puppies!!!

  5. Larfin Jackarse
    Aug 7th, 2009 at 4:02 am

    @coconutnut, why would I want teeth on my amputated limb? (but it would be cool looking!)

  6. Dr Fluroescent Willy
    Feb 8th, 2010 at 11:15 pm

    LOL Kalel, my worst nightmare.


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