YesButNoButYes blog has a post about anti-drug PSAs that look like they were made by people who were under the influence themselves!
The post includes such gems PSAs by Hanna-Barbera, Pee Wee Herman (I half expected him to giggle by the end), and the Teenage Mutant Ninja Turtles.
Link - via Rue The Day!
I've always loved the "pusher" mentality of PSA's. If some thug dragged me into a back alley and forced-injected Heroin into my arm, I'd definitely be back for more!