"Fat Enzyme" Explains Why Some People Never Get Fat

Ever wonder why some people can eat anything they want and never gain weight? UCSF (my alma mater!) researcher Robert Farese and colleagues have found that it may just be the absence of a "fat enzyme":

The enzyme, MGAT2, determines whether dietary fat is used to generate energy or stored under the skin around the waist. The discovery of its role could be the key to preventing obesity, diabetes and heart disease

Scientists found that mice missing the gene for MGAT2 were able to feast on a high fat diet without becoming flabby or overweight.

Mice lacking MGAT2 were also protected against glucose intolerance - a precursor to diabetes - high cholesterol and a build up of fat in liver cells.


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Talking about dentistry. If I had not had my teeth fucked up by the various dentist's I would be able eat better.

Now all my food is pureed and I have nerve damage in my face and in constant pain all down to the damn dentist.
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Great post about some promising research. Let's hope this can quickly be translated into something that will help slow the type 2 diabetes epidemic that is raging across the U.S. and much of the developed world. We write about related issues at http://dentistryfordiabetics.com/blog.

- Charles Martin, DDS
Founder, Dentistry For Diabetics
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