Scientists Found Proteins That “Direct” Own Evolution. Maybe.

By Alex in Science & Tech on Nov 13, 2008 at 3:36 am

A team of Princeton University scientists analyzed proteins involved in energy production of cells and discovered that they have the ability to control their own evolution:

"The discovery answers an age-old question that has puzzled biologists since the time of Darwin: How can organisms be so exquisitely complex, if evolution is completely random, operating like a ‘blind watchmaker’?" said Chakrabarti, an associate research scholar in the Department of Chemistry at Princeton. "Our new theory extends Darwin’s model, demonstrating how organisms can subtly direct aspects of their own evolution to create order out of randomness." [...]

Chakrabarti and Rabitz analyzed these observations of the proteins’ behavior from a mathematical standpoint, concluding that it would be statistically impossible for this self-correcting behavior to be random, and demonstrating that the observed result is precisely that predicted by the equations of control theory. By operating only at extremes, referred to in control theory as "bang-bang extremization," the proteins were exhibiting behavior consistent with a system managing itself optimally under evolution.

I’m a little fuzzy on how the self-correcting behavior is transmitted in the germline … Link – via io9


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  1. Rocky Rook
    Nov 13th, 2008 at 7:05 am

    There really is no randomness in the universe. Everything has a purpose.

  2. noahstrickland
    Nov 13th, 2008 at 8:40 am

    hmmmm…I wonder if Jesus knows about this?

  3. MENLOHEAVYWEIGHT
    Nov 13th, 2008 at 10:36 am

    How can they say that evolution is complety random, evolution tailors the gene pool torwards sustainabilty so at least in that one sense you can say that evolution is what causes the order in the universe toward a specific goal.

  4. bleg
    Nov 13th, 2008 at 11:14 am

    PZ Meyers gives an excellent commentary on this half-baked theory (much better than I could, especially at this hour!) Please go read most excellent post: http://scienceblogs.com/pharyngula/2008/11/prediction_selfpromoting_hy pe.php

  5. silentwatcher24
    Nov 13th, 2008 at 11:20 am

    Could you imagine being able to control directly how the human race could evolve… We’d so be able to fly, and have 10 arms, and other random, awesome things.

  6. CelticCatEyes
    Nov 13th, 2008 at 12:07 pm

    The mechanism they may have found or been talking about is what developmental researchers have already acknowledged in humans, that genes don’t just send out commands from an impenetrable biological safe, but that the environment can send information back into the genetic system and provide information about how genotype should influence phenotype.

    To extend Darwin, as certain individuals develop, the ones who have genotypes which are able to produce phenotypes successful in the environment will be able to reproduce, ensuring that their specific gene & environment interaction patterns are available for the next generation in that location. (I think) changes to the genotype will probably occur (over time) during mating with other successful individuals.

    So, in much more simple life forms, it may appear as if they are ‘choosing’ to evolve certain ways, but it may be something more along these lines…And they’ve found a model to show us exactly how it works.

    http://www.uncg.edu/psy/courses/calogan/438/content/Gedev.html

  7. cheechman85
    Nov 13th, 2008 at 1:47 pm

    “Woosh” going straight over my head.

  8. Athon
    Nov 13th, 2008 at 5:19 pm

    It’s less ‘directed evolution’ and more of a feedback mechanism. As CelticCatEyes said, it’s the environment feeding back on the changing of genes.

    In some cases, you want a lot of variation. In others (such as in the proteins directing the electron transport chain in your cells ‘batteries’ – the mitochondria), changing what works so well isn’t a smart idea. These proteins are a feedback mechanism that keeps these genes working as they should, if I understand it correctly.


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