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	<title>Comments on: Strange Hangover Cures</title>
	<atom:link href="http://www.neatorama.com/2008/01/01/strange-hangover-cures/feed/" rel="self" type="application/rss+xml" />
	<link>http://www.neatorama.com/2008/01/01/strange-hangover-cures/</link>
	<description>The Neat Side of the Web</description>
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		<title>By: S.motion</title>
		<link>http://www.neatorama.com/2008/01/01/strange-hangover-cures/comment-page-1/#comment-383404</link>
		<dc:creator>S.motion</dc:creator>
		<pubDate>Thu, 10 Jan 2008 07:11:16 +0000</pubDate>
		<guid isPermaLink="false">http://www.neatorama.com/2008/01/01/strange-hangover-cures/#comment-383404</guid>
		<description>Of course, if the dehydrogenase actually refers to a blend of both alcohol dehydrogenase *and* acetaldehyde dehydrogenase, then they’d have a modestly useful product. Alcohol detoxification via these two enzymes does occur in the stom\ach (in men only - women lack the enzymes in their stomachs. Both genders, however, do the majority of metabolism in the liver. However, this difference is the reason why men can generallly drink more). Anyway, if you had a product containing both enzymes in 
useful quantities, it would probably allow you to drink more Grange Hermitage than usual before leaving the pub for the night….Of course, as you’ve suggested, it’s more likely they’ve only included one of the dehydrogenase compounds.
Another possibility, rather than them having included alcohol dehydrogenase in their product, is if they’d included solely 

aldehyde degrogenase instead. As it’s the acetaldehyde which makes you feel so awful when you’ve been drinking heavily, additional enzyme could at least help make you feel a it better. It would do nothing, though, to hasten the removal of alcohol from your blood stream per se. In any case, I’m not sure if this would be viable given that once alcohol has been metabolised to acetaldehyde in the liver, I don’t think gastric metabolism would play a major role in detoxifying acetaldehyde to acetic acid.
Bottom line: if someone can come up with a pill that contains both enzymes in useful quantities - I’d be willing to bet that 
it would have some effect. That doesn’t seem to be the case here though, does it…</description>
		<content:encoded><![CDATA[<p>Of course, if the dehydrogenase actually refers to a blend of both alcohol dehydrogenase *and* acetaldehyde dehydrogenase, then they’d have a modestly useful product. Alcohol detoxification via these two enzymes does occur in the stom\ach (in men only &#8211; women lack the enzymes in their stomachs. Both genders, however, do the majority of metabolism in the liver. However, this difference is the reason why men can generallly drink more). Anyway, if you had a product containing both enzymes in<br />
useful quantities, it would probably allow you to drink more Grange Hermitage than usual before leaving the pub for the night….Of course, as you’ve suggested, it’s more likely they’ve only included one of the dehydrogenase compounds.<br />
Another possibility, rather than them having included alcohol dehydrogenase in their product, is if they’d included solely </p>
<p>aldehyde degrogenase instead. As it’s the acetaldehyde which makes you feel so awful when you’ve been drinking heavily, additional enzyme could at least help make you feel a it better. It would do nothing, though, to hasten the removal of alcohol from your blood stream per se. In any case, I’m not sure if this would be viable given that once alcohol has been metabolised to acetaldehyde in the liver, I don’t think gastric metabolism would play a major role in detoxifying acetaldehyde to acetic acid.<br />
Bottom line: if someone can come up with a pill that contains both enzymes in useful quantities &#8211; I’d be willing to bet that<br />
it would have some effect. That doesn’t seem to be the case here though, does it…</p>
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	<item>
		<title>By: NutSak</title>
		<link>http://www.neatorama.com/2008/01/01/strange-hangover-cures/comment-page-1/#comment-373446</link>
		<dc:creator>NutSak</dc:creator>
		<pubDate>Wed, 02 Jan 2008 16:28:57 +0000</pubDate>
		<guid isPermaLink="false">http://www.neatorama.com/2008/01/01/strange-hangover-cures/#comment-373446</guid>
		<description>Drink lots of water before going to bed...and take a vitamin b pill.</description>
		<content:encoded><![CDATA[<p>Drink lots of water before going to bed&#8230;and take a vitamin b pill.</p>
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	<item>
		<title>By: algonkin</title>
		<link>http://www.neatorama.com/2008/01/01/strange-hangover-cures/comment-page-1/#comment-373363</link>
		<dc:creator>algonkin</dc:creator>
		<pubDate>Wed, 02 Jan 2008 15:02:44 +0000</pubDate>
		<guid isPermaLink="false">http://www.neatorama.com/2008/01/01/strange-hangover-cures/#comment-373363</guid>
		<description>That link will be useful for me ;)</description>
		<content:encoded><![CDATA[<p>That link will be useful for me <img src='http://www.neatorama.com/wp-includes/images/smilies/icon_wink.gif' alt=';)' class='wp-smiley' /> </p>
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	<item>
		<title>By: Alex</title>
		<link>http://www.neatorama.com/2008/01/01/strange-hangover-cures/comment-page-1/#comment-372880</link>
		<dc:creator>Alex</dc:creator>
		<pubDate>Wed, 02 Jan 2008 05:39:58 +0000</pubDate>
		<guid isPermaLink="false">http://www.neatorama.com/2008/01/01/strange-hangover-cures/#comment-372880</guid>
		<description>Well, the draconian American justice system (when it comes to drug offenses) is no laughing matter either - that&#039;s why it&#039;s best just to waste your time reading Neatorama. ;)</description>
		<content:encoded><![CDATA[<p>Well, the draconian American justice system (when it comes to drug offenses) is no laughing matter either &#8211; that&#8217;s why it&#8217;s best just to waste your time reading Neatorama. <img src='http://www.neatorama.com/wp-includes/images/smilies/icon_wink.gif' alt=';)' class='wp-smiley' /> </p>
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	<item>
		<title>By: VonSkippy</title>
		<link>http://www.neatorama.com/2008/01/01/strange-hangover-cures/comment-page-1/#comment-372855</link>
		<dc:creator>VonSkippy</dc:creator>
		<pubDate>Wed, 02 Jan 2008 05:13:57 +0000</pubDate>
		<guid isPermaLink="false">http://www.neatorama.com/2008/01/01/strange-hangover-cures/#comment-372855</guid>
		<description>Alcohol poisoning is no laughing matter - that&#039;s why it&#039;s best just to smoke pot (which has an astronomically high LD50 when compared to alcohol).</description>
		<content:encoded><![CDATA[<p>Alcohol poisoning is no laughing matter &#8211; that&#8217;s why it&#8217;s best just to smoke pot (which has an astronomically high LD50 when compared to alcohol).</p>
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	<item>
		<title>By: Dave</title>
		<link>http://www.neatorama.com/2008/01/01/strange-hangover-cures/comment-page-1/#comment-372141</link>
		<dc:creator>Dave</dc:creator>
		<pubDate>Tue, 01 Jan 2008 14:45:05 +0000</pubDate>
		<guid isPermaLink="false">http://www.neatorama.com/2008/01/01/strange-hangover-cures/#comment-372141</guid>
		<description>Prevention is the best medicine. 

While that may be too late for some on the first morning of the year (you do have my sympathy!) think about it next time. It is possible to have a good time and enjoy a drink or two without getting totally blasted.</description>
		<content:encoded><![CDATA[<p>Prevention is the best medicine. </p>
<p>While that may be too late for some on the first morning of the year (you do have my sympathy!) think about it next time. It is possible to have a good time and enjoy a drink or two without getting totally blasted.</p>
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