Placenta Fools the Immune System by Acting Like a Parasite

Scientists had just discovered how placenta avoid being attacked by the mother's immune system: it fools the body's defenses by acting like a parasitic worm!

The placenta plays a vital role in pregnancy, acting as a link between the mother and foetus and providing it with essential nutrients.

However, as both the placenta and foetus have a different genetic make-up from the mother, in theory they are at risk of attack from her immune system.

The researchers already knew that the placenta secreted a small protein - neurokinin B (NKB) - which is found in significantly higher levels in mothers when pre-eclampsia develops. [...]

However, they found that the placental form of the protein did not react in the same way as the form they had been using in the laboratory.

It was clear that a modification was occurring during the synthesis of the protein by the placenta. Further investigation revealed that placental NKB contained the molecule phosphocholine, which is used by the parasitic nematode worm to avoid attack by the immune system of the host in which it lives.

Link


interesting, this could pave the way for the end of immune surpressants for transplant recipients.

Just hope you don't need a transplant then get nematode worms.

As the cure for the worms would flucsh the transplant too.
Abusive comment hidden. (Show it anyway.)
Exactly, Johnald.

Kinda silly to suggest that the placenta "acts like a parasite," when surely the parasite is, in fact, acting like a placenta. There's no reason we would evolve "software support" for a parasite (in fact, plenty of reasons not to), but clearly placentas are, you know, important. Biologically. What with reproduction and all. Just sayin'.
Abusive comment hidden. (Show it anyway.)
Clearly "the parasite is, in fact," NOT " acting like a placenta"... last time I checked, MEN don't get placentas but they still get plenty of parasites.
Abusive comment hidden. (Show it anyway.)
Login to comment.
Click here to access all of this post's 6 comments




Email This Post to a Friend
"Placenta Fools the Immune System by Acting Like a Parasite"

Separate multiple emails with a comma. Limit 5.

 

Success! Your email has been sent!

close window
X

This website uses cookies.

This website uses cookies to improve user experience. By using this website you consent to all cookies in accordance with our Privacy Policy.

I agree
 
Learn More